College Football Best Bets (9/27/25)

Author: Dylan Lieck | September 27, 2025 | 8:47 A.M. CST

I gave out 3 plays already early in the week. We’re going to add an additional play here for the early slate Saturday.

Best Bet: Pittsburgh +3.5 vs. Louisville

Pick: Pittsburgh +3.5

Play Rating: 2-Star